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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

去年世锦赛打破男子1500米自由泳世界纪录,孙杨就被认为是中国男子游泳在伦敦实现历史性突破的希望所在。即将开始的伦敦奥运会,孙杨将参加200米、400米和1500米自由泳三项.去年世锦赛孙杨在400米自由泳中不敌朴泰桓屈居亚军,因此他发誓要在伦敦复仇。相比而言,孙杨在1500米的夺金把握更大...
Theresa May, the new British prime minister, earns 143,462 pounds ($186,119) a year. That includes her salary as a member of parliament, which is 74,962 pounds ($97,256) a year.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: 广东:唤醒“沉睡”的土地
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

去年此时,罗丝·麦高恩以强奸罪控告制作人哈维·韦恩斯,在娱乐圈引发轩然大波,众多控告纷至沓来。
As the title suggests, the show also features the mothers of the pupils and the way that they often pit their children against each other.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

单词posture 联想记忆:

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

当支持者在周一早些时候涌向总督大楼,一人高喊,"今天,新的波多黎各开始了!" 随着其他人的欢呼,包括那些拿着美国国旗的群众。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

美国电影学会年度电影奖
大多数大宗商品的价格自2016年2月以来有所回升,单位价格的同比降幅已收窄至约5%。
但是,海外机构投资者表示,随着中国经济增长放慢,香港房地产市场已经过热,正在进入调整阶段。
The circular also stressed zero tolerance for cheating.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

It's impossible to list every woman who's ever existed, this list obviously be restricted to women who've achieved a fair level of celebrity. These are the hottest women celebrities of 2015.
1.Under no circumstances should you ask your taxi driver how excited he is about having the Olympics in London this summer. It's not that he will be reluctant or embarrassed to offer a personal opinion on the matter. That is not the problem at all.
北极和南极海冰量均降至历史最低水平
Many years before Bryan played "Walter White" on Breaking Bad, he and his brother worked in a restaurant in Florida. The head chef was a very mean man. In a 2011 podcast for Marc Maron, Cranston described him saying "No matter how nice you may have been to him, he hated you." Not surprisingly, all the wait staff routinely discussed how they wanted to kill him. Cranston says it was "all they talked about!"

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 国内LED企业加速拓展新兴市场
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

泰晤士高等教育世界大学排名的编辑菲尔·巴蒂说,“学校的全球发展前景是一个名牌大学的重要标志之一。顶尖大学聘请来自世界各地的教师,吸引来自全球有极高天分的学生,并能与所有的一流专业合作——不管是哪个国家的。”

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

Ellen Johnson Sirleaf, 72, became Africa's first democratically elected female president in 2005. The Nobel Committee praised the Liberian leader for her efforts to secure peace, promote economic and social development and strengthen the position of women.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Americans are celebrating Columbus Day Monday.Columbus Day is a federal holiday observed on the second Monday in October, marking the anniversary of the arrival of Christopher Columbus to the Americas. Columbus, an Italian explorer sailing under the Spanish flag, led four expeditions to the New World, but never accomplished his original goal -- to find a western ocean route to Asia. Instead, Columbus ushered in a new era in world history by opening up the Americas to exploration.
According to the National Business Daily, the 16 listed banks plan to return 356.2 billion yuan to shareholders as cash dividends in 2015, a decrease of 8.3 billion yuan from the previous year.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

With the right tools in place, you’ll find yourself more productive and efficient.
Nirvana in Fire unexpectedly achieved a tremendous success, rising like a star among the TV dramas in the fall of 2015. Also adapted from an online novel of the same name written by Hai Yan, the adaptation for the first time found its way on the screen in September 2015. Staring Hu Ge and Liu Tao, the series shows a talented military strategist endeavoring to clear his name through continuous fights. The fictional characters and dynasty let the adaptation smartly avoid being criticized for not sticking to historical accuracy. And the drama`s delicate internal settings and impeccable storyline were highly praised by the audiences.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

2、冷静自若。007总是很平静。(对男女来说都有用)。即便是在死到临头的时候,也很冷静。这就是性感啊。邦德从不慌张失措。你没见过邦德腿发软手发抖吧。他讲话时语速慢而谨慎,从不乱阵脚。这些都是极富魅力的品质,遭遇劲敌面不改色-这很容易让女人心动不已。他从不向女人表白个不停,就让她们猜不透,搞不懂,这样更加有吸引力。邦德不常微笑也为他的性感加分,因为有幸福感的男人吸引不了女人。007的肢体语言很强势,阳刚血性,从不畏惧;007从不喋喋不休,让他更加优雅;007从不懒散,挺拔的体姿不仅增加自信心,还有力量感,看起来更强壮(身着燕尾服与恶棍搏斗看起来更有档次)。
土耳其部长们近来一直在欧洲各地的土耳其社区举行集会,以争取海外土耳其人对埃尔多安发起的宪法改革的支持——土耳其将于下个月就修宪举行公投。

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 双十一家居电商能否再创奇迹?
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

单词repertoire 联想记忆:
n. 好客,殷勤,酒店管理
有时,它是英语中最可怕的字眼之一。但是当机会在你的职业生涯中出现时,你应该准备好说出这个字眼:Yes。
这一周发生的事情对国王来讲是火车事故:毫无说服力的否认,考辛斯在全明星周日交易的时刻,可怜的交易回报价值,

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

总的来说:世界最大经济体任然可以入常运转就如同沙漠中的绿洲就算有末世预言宣称那样的日子已经远去了。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

顺便说一句,伦敦的自行车租赁制度再简单不过了:走到任何一个租车点,刷卡付费就可以带走一辆自行车。当你使用完毕时,把车丢在附近的河里就行。这些自行车都是一次性的!
'Cutie and the Boxer' was hardly noticed by the movie-going public, but a list of fine films isn't a rundown of box-office triumphs. The reach of Zachary Heinzerling's debut feature-length documentary is equaled by its grasp. On the surface it's about nothing more-or less-than a troubled marriage that has somehow managed to last 40 years. Beneath the surface, then startlingly out in the open, is a history of rivalry (both husband and wife are artists), enmity, reluctant devotion and, most startling of all, enduring love.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

2010年,马丁飞行器公司推出的喷气背包号称"世界上第一个盗版喷气背包"。这个喷气背包甚至还被列入《时代周刊》"2010年度50强发明"之一,因为众所周知世界上第一个喷气背包是在1958年发明的,且自1981年来一直在发展。喷气背包由温德尔·穆尔设计,他是贝尔空间系统公司的研究员。温德尔设计的喷气背包的早期模型飞行高度可达5米(16英尺),飞行时间为3分钟。这一点引起了美国军队的注意,美国军队便为这一项目投资了15万美元。后来,还特地为美国军队做了些试飞飞行器,也为肯尼迪总统做了飞行器。之后,因为飞行时间和飞行距离有限,美国军队取消了对这个项目后续研究的投资。美国航天局也想用喷气背包为阿波罗11号任务做支援,以防登机舱出故障。但之后还是改变了想法,改用了月球车。贝尔经历了这个挫折后,停止了对飞行器的进一步研究。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

我们要求FlightAware对航班抵达延误情况进行统计,而不是航班出发延误情况,因为有时候,航空公司可以让飞机在空中飞行期间追回地面上失去的时间。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

A Honda executive privately attributed much of its troubles on “bad luck,” as opposed to shoddy business practices or deliberate misbehavior on anyone’s part. Perhaps. The company’s leadership is certain to check, double-check and lock down its systems and processes to ensure the level sinks no lower on its reservoir of good will.
奥巴马赢得了第二场辩论挽回颓势。虽然他也赢得了第三场,外交政策并不是选民关注的主要问题,这不大可能导致较大的选票波动。
电池电力可能最终被证明是一种过渡性技术。最近电池成本的降低速度已经放慢了,特斯拉曾经承诺要在2017年生产出价格在35,000美元左右的Model 3。要实现这个目标,特斯拉的电池成本需要下降30%。相比之下,丰田(Toyota)最近的举动非常出人意料。它与特斯拉签订的电池供应协议即将期满,但丰田并未续约,而是准备加倍投入研发氢燃料电池。燃料电池的成本下降速度要快于普通电池。而且燃料电池的拥趸们认为,车主肯定会更喜欢充电速度相对更快的燃料电池,而不是要为充电等上好几个小时。
Twenty-something show

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

要实现有效的电子邮件营销,可不只是偶尔发一封电子文宣邮件那么简单。要想构建一套有效的电子邮件营销战略,你需要一个功能齐全的工具。MailChimp似乎是市面上最佳的此类系统,它提供了各种典雅直观的电邮广告模板、先进的分段功能和营销自动化功能。
“If you were going to be betting, you would bet its going to be warmer than 2015,” said Mr Karl.
海莉·威廉姆斯依然是颇有影响力的重要存在,一位不论是低声哼唱还是大声呐喊都能令人信服的歌手。她直言不讳的勇气几乎使你忘记《欢笑过后》记录的是她对这个世界的厌倦。
谷歌的品牌价值现在超过了1090亿美元,比苹果公司要高大约20亿美元,这使其成为了全世界最赚钱的公司。
Vawter 使用仿生腿在芝加哥一栋高楼里向上爬了103个阶梯,但是仿生腿的设计者们仍然在尝试提高它的性能。为了使它能适用于日常生活,设计者们必须让它更轻更薄。它的衍生品(充气仿生腿)可以满足陆军对于仿生腿的阶段性目标——行走一万步不用充电。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: 北京将严查个人贷款资金违规购房
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

8.The Big Bang Theory Whiteboard Has Real Equations
以下是CareerCast公布的完整榜单:

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

n. 准学士学位获得

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

巴里摩尔的病情基于米歇尔·菲利普斯的真实生活,她的头部在在两次机动车事故中受伤,记忆只能维持24小时。桑德勒用录像带,菲利普斯则是用便利贴和手机(对她而言还真时髦)撑了23年。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

['tmpi?n?ip]
The rest of them, he goes over quickly:
About 71.9 million units were shipped in the period, which includes the key Christmas shopping season. IDC said the decline was the worst since it started tracking PC shipments.
Barrymore's condition was based on the real life of Michelle Philpots, who suffered head trauma in two separate motor vehicle accidents, which left her with a 24-hour memory. Rather than using Sandler's tapes, Philpots has survived for over 23 years using Post-it notes and her (amazingly modern, from her perspective) mobile phone.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

China’s forex reserves — the world’s largest — have long been seen as the ultimate guarantor of financial stability, since they can be used to hedge against capital flight or to bail out domestic financial institutions struggling with a rise in bad debts.
“然而,考虑到政策紧缩的延迟影响,以及房地产市场降温将在未来数个季度压制中国对大宗商品的需求,我们怀疑出口的增长势头是否还能维持下去。”
排名榜单前10的富人中有4人--马化腾,马云,丁磊(中国游戏开发商网易首席执行官),雷军(智能手机制造商小米创始人)来自TMT(电讯、媒体和技术)领域。
Some delegated the task:

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
From the themed collection: 住宿保障:启动 酒店房价监测
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

A major disruption still could push oil higher, but potential oversupply makes even that less likely. Emerging-market demand once kept supply so tight that any disruptions led to striking price moves, said Ole Hansen, head of commodity strategy at Saxo Bank.
['t?nl]

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
From the themed collection: 长三角一体化发展规划发布渐近
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Starting a business can wreak havoc on the owner’s personal life. While all the above tips are necessary for success, taking care of yourself mentally and physically is also imperative. Exercise, sleep and diet play a central role in ensuring you implement these policies successfully. All of them drive attitude, motivation and relationships.
凭借这场胜利,金州勇士队追平了由1957-1958赛季的波士顿凯尔特人队创造的卫冕冠军赛季开局14连胜纪录。而勇士队也是成为在NBA历史上,仅有的五只以14胜0负开局的球队。接下来,他们将会作客丹佛,力争在周日将纪录继续保持下去。
China's online retail volume is expected to outperform the rest of the world by reaching four trillion yuan (618 billion USdollars) this year, Commerce Minister Gao Hucheng said Sunday.
中国保险企业2016年上半年利润出现大幅下滑。
“网络反腐大部分靠文字、照片、视频等,从这些途径‘揪’贪官,容易流于表面化。”

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Morocco is a gateway to Africa. Major tourism cities in the North African kingdom include the capital of Rabat, Casablanca – the country's largest city - Marrakesh and Agadir.
现在达洛伊西奥还不负责管理他的收入。他坚称说,我太年轻了,还不懂如何发挥其价值。我没有房贷,我才17。对我来说100英镑就是个大数目了,这就是我对钱的大致概念。尽管他无法对Summly的售价置评,但当我逼问他未来打算如何支配的时候,他说他在考虑以后也许可以用所发之财来做一名天使投资人。在他身边,似乎没人觉得这份钱会毁掉他或者他会挥霍钱财浪费人生。戴安娜说,孩子很踏实,很有冲劲儿,他不会停止奋斗的。
13. Even Better In October, The Los Angeles Times reported that the Equal Employment Opportunity Commission was investigating gender discrimination in the industry, just as the American Civil Liberties Union requested state and federal agencies do after it conducted its own inquiry.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

China is now home to over 80,000 trade markets and total retail sales of consumer goods would reach 30 trillion yuan this year with consumption contributing to about 60 percent of total GDP growth, Gao said.
在这部暂未定名的电影里面,两段交错的三角恋,偏执,背叛等元素与音乐场面相互映衬。参演此片的有克里斯蒂安·贝尔(ChristianBale)、凯特·布兰切特(Cate Blanchett)、迈克尔·法斯宾德(Michael Fassbender)、瑞恩·高斯林(RyanGosling)、鲁妮·玛拉(Rooney Mara)以及娜塔丽·波特曼(Natalie Portman.)。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

It's a travel pillow that bends to support your head in any position.
5. Hong Kong, China-A junk boat set against the famous skyline might be the iconic shot of Hong Kong, but Lonely Planet picked the territory for its natural heritage miles away from Victoria Harbor.
一位被录取的学生告诉《哈佛深红报》,这些表情包来自哈佛2021届学生的脸书私聊小组,他们在这个群组里分享一些尖酸刻薄的笑话,“被哈佛录取不代表我们就不能开玩笑”。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

8. It’s never too late to start.
My heart is my New Year present to you.我的心就是我奉献给你的新年礼物。
However, significantly fewer women (59 per cent) occupy positions as department heads or above than men (68 per cent) three years after graduation.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 七部委联合打击炒房客黑中介
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

This year's lift was slower than the 6.5% rise in 2016, which is attributed to moderating economic growth and a rapidly aging society.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 家居品牌联盟首建总部基地
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

"As robotics is expanding into nearly every industry, Chinese robot makers should realize the gap between them and foreign brands, take advantage of China's robotics development boom and learn from foreign experience to help China grow from the world's largest robot market into a robot manufacturing power," said Qu.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

2018年底石油价格会超过每桶70美元吗?
给你特别的祝福,愿新年带给你无边的幸福、如意。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

单词remembrance 联想记忆:
The contiguous United States set a temperature record in 2012, a year of scorching heat waves and drought. But, mostly because of the unusual chill in the East, 2014 was only the 34th warmest year on record for the lower 48 states.
China's box office sales have increased from 1 billion yuan to 40 billion yuan in the past decade as the industry has adopted more market-oriented reform measures.
4. 2012年搞笑诺贝尔奖之神经科学奖

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Will the housing sector adjust easily to higher interest rates?
那么,于汽车业而言,2015年又意味着什么?以下是一些有根据的猜测。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

I'm assuming they'll end up around the No. 10 pick at this point; it's hard to get an instant franchise player that low, and New Orleans doesn't have all the time in the world.
他补充说道:“我很兴奋能有机会重返中国,并享受这个国家的文化以及把NBA现场比赛的激动直接带给中国球迷。”

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

1. Am I taking care of myself? Sometimes we get so wrapped up in taking care of others that we forget to take care of ourselves. It can be so easy to leave ourselves behind.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

['letis]
周二,她在给客户的一封信里提出了下面几个观点,令我耳目一新:
考辛斯的交易有资格作为一枚重磅炸弹,猛龙用两笔大交易确立了他们东部冠军挑战者的位置,以及,在另外的故事情节中,西部最后一个季后赛席位的争夺将愈演愈烈。
Anxiety has been fanned by the build-up of corporate debt in emerging markets, which doubled between 2008 and 2014 and has been one of the fastest growing areas of the global bond market.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

2016年空前的海外收购潮消耗了中国大量外汇储备,随后监管部门开始严格限制境外交易。今年8月,中国政府出台了新框架,鼓励那些符合北京战略重点的交易,并限制涉及娱乐、体育和豪宅等方面的交易。
“It was the real 'I have to do this' moment,” he says.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
From the themed collection: 曾经膨胀的楼市心态 复归理性
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Japan, ranked No. 5 overall, is the top performing Asian country. It ranks No. 5 in Movers and No. 1 as the most forward-looking country.
10.你真的很明显,好吧?
So the messaging apps have gotten creative. Tango, for example, inserts ads within a user’s messaging “inbox.” WeChat, a popular Chinese app that is owned by Tencent, makes money through games, stickers (which are similar to emojis), and mobile commerce. Kik offers a feature that some are calling “chatvertising,” where users hold conversations with chat-bots powered by brands like Funny or Die and Moviefone.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 家居行业兴起30年 公益之路一起走
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

7 August
大多数成功的创业者都遵循类似的模式,并且具备类似的基本特质。无数在线文章和图书宣称掌握了商业成功的秘诀,但事实上其中大多数都可以归结为几个相同的要点。
报告指出,浙江省的杭州市以及广东省的深圳市通过车辆限制及更好的道路连接等方式,在提升交通状况上取得了最大的进步。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
From the themed collection: 长租公寓“野蛮生长”如何规范
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

单词channel 联想记忆:
英国的一个收集全球气温纪录的科学小组也将在未来几周内提交报告。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

她最近成了她的父亲、前总理纳瓦兹·谢里夫(Nawaz Sharif)的左膀右臂。但腐败指控给她的迅速崛起蒙上了阴影。
The annual national civil service exam kicked off last Sunday, and some recent hot topics - such as college graduates starting their own businesses and the Yutu (Jade Rabbit) lunar rover - appeared in the exam questions.
Frankly, this is unlikely to be ready in time for next year, but we'll include it just in case. The second film from Laszlo Nemes, who won the foreign language Oscar earlier this year for Son of Saul, is a coming-of-age drama set in Budapest just before the first world war.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

美国的药品支出费用约占总量三分之一,据艾美仕研究所专家估计,2014年这个数值将上升11.7个百分点。据报道,美国的药品支出费用价格特别高,但制药商解释说这是由于研制新药的成本猛增。
中国约占世界黄金产量的15%,这个比例高于沙特占石油市场的比例。但自2016年以来,中国当局收紧了对黄金开采的审查,导致中国的小型金矿纷纷关闭。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

"Metro-Goldwyn-Mayer Inc. ('MGM') today announced that the secured lenders voting in the Company's solicitation process have overwhelmingly approved its proposed plan of reorganization ('Plan'). MGM will now move expeditiously to implement that Plan, which will dramatically reduce its debt load and put the Company in a strong position to execute its business strategy. MGM is appreciative of the lenders' support."
I know this takes time, but it'll ensure you really know your stuff. And that's why you're going to school. Right?
Yes. Mr Modi’s overnight ban on using high-value bank notes was a big shock, and seriously disrupted the economy. But it delivered rich political rewards, bolstering the premier’s image as a decisive leader willing to take tough action against corruption. With the next general elections due in 2019, Mr Modi will be tempted to deliver one more big bang to dazzle voters. Watch out for dramatic action against wealthy individuals holding properties in others’ names to hide their ownership.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

尽管詹姆斯和费德勒在工资和薪水上要少一些(相比于C罗和梅西),但是这两人去年的代言费是最高的,其中17次大满贯得主费德勒去年代言收入达到了4100万英镑。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

女士们,我们都接到这样的警告,你将会如何回复呢?
6. The 2012 Ig Nobel Prize for Literature

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

国家统计局表示,这一比例虽然与经济合作与发展组织成员国2.4%的平均水平还有差距,但已超过欧盟2.08%的平均水平。
祝大家2015年好运。(财富中文网)

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

10) You’re Right: Want to get someone’s attention? Tell him that he’s right. Once you yield the high ground, it’s much easier for the other party to swallow that the right plan and sentiment can’t always overcome the absurdities and restraints we face every day.
adj. 最初的,原始的,有独创性的,原版的

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

单词receptive 联想记忆:
它把孩子的重量从您的后背转移到肩膀和腰腹部。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

In a rigorous analysis of Dutch financial records, Koudijs and Voth conclude that the only real difference between the pessimists and the optimists was whether they had gone through a harrowing personal experience. Koudijs compares it to the behavior of people who lived through the Great Depression, and who avoided financial risk for decades after trauma had passed.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

谷歌公司一名发言人在上周三时表示,该公司意识到“这是一个错误,哈维尔是无心之失”。
It remains the world's largest country and the largest oil producer. It retains its permanent seat on the UN Security Council. Its nuclear arsenal (in Cold War times one of five countries, but now one of nine) has been progressively modernised. Sustained increases in defence spending have brought it close to its goal of escalation dominance in local and regional war.
越南昆岛——越南昆岛曾是臭名昭著的昆岛监狱所在地,由16座独立的小岛组成;现在,它的美景及海鲜正变得越来越有名气。
据中新网报道,德国工商总会外贸主管沃尔克·特赖尔表示,2016年下半年从德国出口到中国的货物量增长非常迅速。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

oDesk和Elance(两家公司正处于并购流程)是两个自由职业者市场,你可以在上面迅速找到、联系并聘请到全球各地的自由职业者。需要一个网站开发员或内容写手?不必雇佣一名全职员工,招募一名自由职业者就可搞定。活跃在这两个市场上的自由职业者多达100余万人。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

Bursts of color are instant energy suppliers. If you can, paint your walls or use furniture and accessories to provide a colorful oomph.
一名校友表示:我们被迫远离了安逸,但获得了独特的体验。
Swift has also been having quite the year, claiming the No. 2 spot with $80 million. More than a year after the launch of 1989—the top release of 2014 with over 3.6 million copies sold—her latest single, “Wildest Dreams,” has ascended to the top of the charts, boosted by a music video with Scott Eastwood. But it was the beginning of her epic 1989 World Tour that placed her so close to the top of this list.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

● “特朗普为想要离开美国的公民提供非洲或墨西哥单程机票”
圣加伦大学校友在毕业3年后的平均年薪增至10.2万美元,去年这个数字为9万美元。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

赢家:雷霆
An employee in the public relations department at Tencent Holdings, operator of a live-broadcast app through which a man received online payments of more than 250,000 yuan ($36,400) from a 13-year-old girl for his singing talent, said the girl might have faked her age when registering.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

“An employee baked a cake with her resignation letter written on top.”

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

It was a rare glimpse into his closely guarded personal life that also put at risk Apple’s brand in less tolerant parts of the world. Mr Cook was driven to take a stand by his experiences growing up in Alabama, where he has talked of seeing discrimination that “literally would make me sick”.
Two bedrooms are on the second floor, including the master, which is part of a suite with a fireplace, a walk-in closet and a balcony overlooking the bay. An office down the hall also opens to the balcony. The other bedrooms are on the third floor. One overlooks the bay through the pediment’s fan window.
巴里摩尔的病情基于米歇尔·菲利普斯的真实生活,她的头部在在两次机动车事故中受伤,记忆只能维持24小时。桑德勒用录像带,菲利普斯则是用便利贴和手机(对她而言还真时髦)撑了23年。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

在这部暂未定名的电影里面,两段交错的三角恋,偏执,背叛等元素与音乐场面相互映衬。参演此片的有克里斯蒂安·贝尔(ChristianBale)、凯特·布兰切特(Cate Blanchett)、迈克尔·法斯宾德(Michael Fassbender)、瑞恩·高斯林(RyanGosling)、鲁妮·玛拉(Rooney Mara)以及娜塔丽·波特曼(Natalie Portman.)。
认为西方民主政体不会受影响将是愚蠢的。
According to the annual Global Trade Protection Report, companies in the US launched 43 anti-dumping cases in 2015 and a further 22 anti-subsidy investigations aimed at securing countervailing duties. The US took the lead in both areas, overtaking India and Brazil, which launched the most cases in 2014 and 2013.
The companies that have tried — and so far failed — to create a sustained ETF boom in Asia say the need for wholesale reform suggests the market will be defined by a protracted effort to convince both the regulators and customers to redraw the scenery.

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 3G互联网优势助力国内建材业腾飞
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

According to Brandi Bennett at HostGator.com,maintaining a blog on a well-hosted website, or volunteering your time and skills, shows instead of tells the community, and thereby builds expertise and trust.
“整个20世纪下半叶,在世界各地,贸易和经济增速都出现了这么大的差异。所有的专业化分工都意味着出口增长快于GDP增长,”威廉姆斯说。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 绿色建材标准推新材料入市
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

The Veterans Day holiday, which pays tribute to all men and women who have served in the U.S. military, dates back to 1919, when President Woodrow Wilson proclaimed November 11 as Armistice Day to celebrate the end of fighting exactly one year earlier in World War One - "the war to end all wars" - between Germany and the allied nations of Britain, France and the United States. The armistice famously went into effect at "the eleventh hour of the eleventh day of the eleventh month."
课程安排:每隔一个周末在芝加哥上课,共计大约18门课程,包括4门选修课。学员在芝加哥住校学习3周,在香港和伦敦分别学习1周。
On the flip side, why do so many JetBlue flights arrive late during the holidays (22 percent)? For one thing, it flies to and from some of the busiest airports in the country, including New York’s JFK, LaGuardia and Newark Airports. And it encounters some of the same issues as Hawaiian does over the Pacific.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

根据美国海洋和大气管理局的数据,美国本土今年1月至11月的气温是有史以来每年前11个月的最高记录。2012年还将超过1998年,成为美国有记录以来最热的一年。
然而,北方高等商学院毕业生的国际化流动程度最高,2014届毕业生有85%曾在国外工作。

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